Well, I can not comment on actual usage because I just received my case today. I received notice of shipping on 9-26 and received it on 10-3, Very quick IMO.
My case is for the iPhone 4 with a Vapor Pro Aluminum Case. I had a pen holder added. The vegetable-tanned leather is a very light beige color that will darken with use and age. I would not call mine huge nor ugly. I would call mine trim, very handsome and high quality. I am very pleased with mine. I would imagine a case to fit the Otterbox Defender would be a small amout larger than mine. I do not think you would be dissapointed at all.
bc